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- Effects of testosterone on coronary vasomotor regulation in males with coronary heart disease.
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- Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and high quality of life.
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In addition, this patient additionally had polycythemia, likely secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the proper coronary artery. Physicians and patients ought to concentrate on the clinical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses might even be helpful in sufferers with angina , have higher ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in males with established coronary artery illness .
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